37.
RichardHorton,
COVID-19 is not a pandemic, 2020.09.26,
https://doi.org/10.1016/S0140-6736(20)32000-6 .
Authur points out that Covid-19 is not a pandemic but a syndemic and so to limit the harm caused by SARS-CoV-2 will demand far greater attention to NCDs and socioeconomic inequality than has hitherto been admitted. Additionally, addressing COVID-19 means addressing hypertension, obesity, diabetes, cardiovascular and chronic respiratory diseases, and cancer so that can truly revive the society.
36.
American Society for Microbiology,
MMR vaccine could protect against the worst symptoms of COVID-19, 2020.06.19 ,
https://www.eurekalert.org/pub_releases/2020-06/asfm-mvc061620.php .
Administering the MMR (measles, mumps, rubella) vaccine could serve as a preventive measure to dampen septic inflammation associated with COVID-19 infection, say a team of experts in this week's mBio, a journal of the American Society for Microbiology.
35.
THE LANCET,
Comprehensive study to date provides evidence on optimal physical distancing, face masks, and eye protection to prevent spread of COVID-19, 2020.06.01,
https://www.eurekalert.org/pub_releases/2020-06/tl-pss060120.php .
This paper says "of all available evidence including 172 observational studies looking at how physical distancing, face masks, and eye protection affect the spread of COVID-19, SARS, and MERS in both community and healthcare settings across 16 countries".
33.
Gharpure R, Hunter CM, Schnall AH, et al. ,
Knowledge and Practices Regarding Safe Household Cleaning and Disinfection for COVID-19 Prevention — United States, May 2020, 2020.06.05,
http://dx.doi.org/10.15585/mmwr.mm6923e2 .
CDC conducted an Internet panel survey which identified gaps in knowledge about safe preparation, use, and storage of cleaners and disinfectants. Approximately one third of survey respondents engaged in nonrecommended high-risk practices with the intent of preventing SARS-CoV-2 transmission, including using bleach on food products, applying household cleaning and disinfectant products to skin, and inhaling or ingesting cleaners and disinfectants.
32.
Georg Wolff, Ronald W. A. L. Limpens, Jessika C. Zevenhoven-Dobbe, Ulrike Laugks, Shawn Zheng,
A molecular pore spans the double membrane of the coronavirus replication organelle, 2020.08.06,
https://science.sciencemag.org/content/early/2020/08/05/science.abd3629 .
The study found a hexameric assembly of a large viral transmembrane protein which formed the core of the crown-shaped complex. This coronavirus-specific structure likely plays a critical role in coronavirus replication and thus constitutes a potential drug target.
31.
University Of Alabama At Birmingham,
Is the COVID-19 virus pathogenic because it depletes specific host microRNAs? 2020.08.14,
https://www.eurekalert.org/pub_releases/2020-08/uoaa-itc081420.php .
UAB and Polish researchers propose that the COVID-19 virus acts as a microRNA "sponge" to deplete miRNA levels in ways that aid viral replication and stymie the host immune response.
30.
Prabhu S. Arunachalam, Florian Wimmers, Chris Ka Pun Mok, Ranawaka A. P. M. Perera,
Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans, 2020.08.11,
https://science.sciencemag.org/content/early/2020/08/10/science.abc6261 .
This article analyes immune responses in 76 COVID-19 patients and 69 healthy individuals and the results highlight molecules such as EN-RAGE or TNFSF14, and their receptors, which could represent attractive therapeutic target against COVID-19.
29.
Pedro M Folegatti, Katie J Ewer, Parvinder K Aley, Brian Angus, Prof Stephan Becker, Sandra Belij-Rammerstorfer, et al.,
Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial, 2020.07.20,
https://doi.org/10.1016/S0140-6736(20)31604-4 .
ChAdOx1 nCoV-19 showed an acceptable safety profile, and homologous boosting increased antibody responses. These results, together with the induction of both humoral and cellular immune responses, support large-scale evaluation of this candidate vaccine in an ongoing phase 3 programme.
28.
Feng-Cai Zhu, Xu-Hua Guan, Yu-Hua Li, Jian-Ying Huang, Tao Jiang, Li-Hua Hou, et al.,
Immunogenicity and safety of a recombinant adenovirus type-5-vectored COVID-19 vaccine in healthy adults aged 18 years or older: a randomised, double-blind, placebo-controlled, phase 2 trial, 2020.07.20,
https://doi.org/10.1016/S0140-6736(20)31605-6 .
This study shows that the Ad5-vectored COVID-19 vaccine at 5 × 1010 viral particles is safe, and induced significant immune responses in the majority of recipients after a single immunisation.
Chinese Society of International Law, in association with Chinese Institute of International Law at China Foreign Affairs University, and National Center for Foreign-related Rule of Law Research at China Foreign Affairs University
Contact: secretary@bigghgg.cn